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REACT4KIDS

Equipe BIPOA, Groupe Cancers osseux

Institut de Biologie Valrose, Nice

 

Membres

• A Schmid-Alliana (DR Inserm)
• H Schmid-Antomarchi (DR CNRS)
• MA Millet (ITA Inserm)
• N Amoretti (PH CHU
• C Cohen (Thésard)
• J Antomarchi-Cannavo (Thésard)
• PA Gaucci (Master2)
• A Rudel (Master2)

 

Thématique de recherche générale en oncopédiatrie

Etudes précliniques et mécanistiques d’immunothérapies associées à d’autres thérapies anticancéreuses pour les tumeurs osseuses primaires (ostéosarcome) et métastatiques (cancers poumon, rein, sein).

 

Collaborations

Pr JM Bouler, Dr B Bujoli, Dr E Verron, Chimistes, CEISAM, Faculté Dentaire, Nantes
Graftis, Partenaire industriel, Aix en Provence
Dr A Dutour, Centre Léon Bérard, Lyon

 

Publications

Percutaneous vertebroplasty in tumoral spinal fractures with posterior vertebral wall involvement: Feasibility and safety.
Amoretti N, Diego P, Amélie P, Andreani O, Foti P, Schmid-Antomarchi H, Scimeca JC, Boileau P.
Eur J Radiol. 2018 Jul;104:38-42. doi: 10.1016/j.ejrad.2018.04.010. Epub 2018 Apr 20.

Understanding the Progression of Bone Metastases to Identify Novel Therapeutic Targets.
Schmid-Alliana A, Schmid-Antomarchi H, Al-Sahlanee R, Lagadec P, Scimeca JC, Verron E.
Int J Mol Sci. 2018 Jan 4;19(1). pii: E148. doi: 10.3390/ijms19010148. Review.

Gallium, a promising candidate to disrupt the vicious cycle driving osteolytic metastases.
Strazic-Geljic I, Guberovic I, Didak B, Schmid-Antomarchi H, Schmid-Alliana A, Boukhechba F, Bouler JM, Scimeca JC, Verron E.
Biochem Pharmacol. 2016 Sep 15;116:11-21. doi: 10.1016/j.bcp.2016.06.020. Epub 2016 Jul 1.

Genetic and pharmacological inactivation of the purinergic P2RX7 receptor dampens inflammation but increases tumor incidence in a mouse model of colitis-associated cancer.
Hofman P, Cherfils-Vicini J, Bazin M, Ilie M, Juhel T, Hébuterne X, Gilson E, Schmid-Alliana A, Boyer O, Adriouch S, Vouret-Craviari V.
Cancer Res. 2015 Mar 1;75(5):835-45. doi: 10.1158/0008-5472.CAN-14-1778. Epub 2015 Jan 6.

Adaptive immune response inhibits ectopic mature bone formation induced by BMSCs/BCP/plasma composite in immune-competent mice.
Bouvet-Gerbettaz S, Boukhechba F, Balaguer T, Schmid-Antomarchi H, Michiels JF, Scimeca JC, Rochet N.
Tissue Eng Part A. 2014 Nov;20(21-22):2950-62. doi: 10.1089/ten.TEA.2013.0633. Epub 2014 Jun 12.

Therapeutic strategies for treating osteolytic bone metastases.
Verron E, Schmid-Antomarchi H, Pascal-Mousselard H, Schmid-Alliana A, Scimeca JC, Bouler JM.
Drug Discov Today. 2014 Sep;19(9):1419-26. doi: 10.1016/j.drudis.2014.04.004. Epub 2014 Apr 14. Review.

CXCR7-mediated progression of osteosarcoma in the lungs.
Goguet-Surmenian E, Richard-Fiardo P, Guillemot E, Benchetrit M, Gomez-Brouchet A, Buzzo P, Karimdjee-Soilihi B, Alemanno P, Michiels JF, Schmid-Alliana A, Schmid-Antomarchi H.
Br J Cancer. 2013 Sep 17;109(6):1579-85. doi: 10.1038/bjc.2013.482. Epub 2013 Sep 3.

 

Contact

Annie.Schmid-Alliana@unice.fr
Heidy.Schmid-Antomarchi@unice.fr